Nebraska vs. Northwestern odds, spread: 2022 college football picks, Week 0 predictions by model that’s 43-31

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The Northwestern Wildcats aim for revenge when they open the 2022 college football season on Saturday. Northwestern faces the Nebraska Cornhuskers in the 2022 Aer Lingus College Football Classic. The Big Ten foes square off in Dublin, Ireland, with Northwestern seeking to return the favor after a blowout 2021 loss to Nebraska. The matchup is the earliest date of a conference game in Big Ten history, and it is the seventh FBS game played in Ireland.

Caesars Sportsbook lists the Cornhuskers as 11-point favorites in Dublin for this 12:30 p.m. ET kickoff. The total number of points Vegas thinks will be scored, or the over/under, is 51.5 in the latest Nebraska vs. Northwestern odds. Before making any Northwestern vs. Nebraska picks or college football predictions, you need to see what SportsLine’s advanced computer model has to say.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six years, the proprietary computer model has generated a stunning profit of almost $3,600 for $100 players on its top-rated college football picks against the spread. It also finished the 2021-22 college football season on a 43-31 run on all top-rated college football side picks. Anyone who has followed it has seen huge returns.

Now, the model has set its sights on Nebraska vs. Northwestern and just locked in its picks and CFB predictions. You can head to SportsLine now to see the model’s picks. Now, here are several college football odds and betting lines for Northwestern vs. Nebraska:

  • Nebraska vs. Northwestern spread: Nebraska -11
  • Nebraska vs. Northwestern over/under: 51.5 points 
  • Nebraska vs. Northwestern money line: Nebraska -440, Northwestern +335
  • NEB: The Cornhuskers outscored opponents by 63 points in 2021 
  • NW: The Wildcats return nine offensive starters 
  • Nebraska vs. Northwestern picks: See picks here.

Featured Game | Northwestern Wildcats vs. Nebraska Cornhuskers

Why Nebraska can cover

The Cornhuskers do lose a four-year starting quarterback in Adrian Martinez, but Nebraska actually has a chance to improve at the position in 2022. Casey Thompson projects as the starter for Scott Frost’s team, and he arrives as a transfer from Texas. Thompson completed 63.2% of his passes for 2,113 yards and 8.1 yards per attempt in split duty last season. He also threw for 24 touchdowns and only nine interceptions, ranking in the top five of the Big 12 in passing efficiency. Nebraska also changed its staff, headlined by Mark Whipple, and the former Pittsburgh offensive coordinator led a top-10 offense in the country in 2021. 

Nebraska’s wide receiver corps is unproven but talented, including transfers in Trey Palmer from LSU and Marcus Washington from Texas. On defense, Nebraska also restocked the cupboard with former TCU defensive Ochaun Mathis, who generated 13 sacks over the last two seasons with the Horned Frogs. Nebraska’s roster talent exceeds Northwestern’s roster talent, and the Cornhuskers dominated the 2021 matchup.

Why Northwestern can cover

Northwestern has revenge on its mind after a blowout loss in this matchup a season ago. The Wildcats should benefit from the shortcomings of Nebraska, including a brutal record in competitive games. The Cornhuskers became the first team in the Associated Press Poll era with nine single-digit losses in a single season in 2021.

The Cornhuskers had one of the worst special teams units in the country last season, and Nebraska produced only 13 takeaways on defense. The Cornhuskers were near the bottom of the Big Ten in sacks and overall havoc creation on defense, making life easier for Northwestern’s sometimes conservative offense. The Wildcats also have a true X-factor in left tackle Peter Skoronski, who many project to be a first-round selection in the 2023 NFL Draft.

How to make Nebraska vs. Northwestern picks

SportsLine’s model is leaning Under on the point total, projecting the teams to combine for 42 points. The model also says one side of the spread hits in well over 70% of simulations. You can only see the model’s Northwestern vs. Nebraska pick at SportsLine.

So who wins Nebraska vs. Northwestern? And which side of the spread hits in well over 70% of simulations? Visit SportsLine now to find out which side of the Nebraska vs. Northwestern spread you need to jump on Saturday, all from the model that has crushed its college football picks, and find out. 



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