College football odds, picks, predictions, best bets for Week 7: Proven model loves Kentucky, Clemson

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The Week 7 college football schedule brings some especially important matchups in the SEC, Big 12 and Pac-12. The latest Week 7 college football odds from Caesars Sportsbook list No. 3 Alabama as a 7.5-point favorite against No. 6 Tennessee, while No. 16 Mississippi State is laying 6.5 points at No. 22 Kentucky. In the Big 12, No. 13 TCU is a 3.5-point favorite against No. 8 Oklahoma State and No. 19 Kansas is a 7-point underdog on the road against Oklahoma.

Over in the Pac-12, No. 20 Utah is laying 3.5-points against No. 7 USC in the latest Week 7 college football spreads. Which college football lines should you be targeting this weekend? Before locking in any Week 7 college football picks on those games or others, be sure to see the latest college football predictions from SportsLine’s advanced computer model.

The SportsLine Projection Model simulates every FBS college football game 10,000 times. Over the past six-plus years, the proprietary computer model has generated a stunning profit of almost $3,000 for $100 players on its top-rated college football picks against the spread. Anyone who has followed it has seen huge returns.

Now, it has turned its attention to the latest Week 7 college football odds from Caesars and locked in picks for every FBS matchup. Head here to see every pick.

Top college football predictions for Week 7

One of the college picks the model is high on in Week 7: No. 4 Clemson (-4.5) goes on the road and covers against Florida State at 7:30 p.m. ET on Saturday. The Tigers feature a ferocious defense, giving up just 64.2 rushing yards per game, which ranks second in the nation. Clemson is coming off an impressive victory on the road against Boston College, holding the Eagles to just three points.

Meanwhile, FSU suffered its second straight defeat after losing 19-17 against NC State. The Seminoles started the season with three consecutive wins, but Mike Norvell’s men have sputtered in recent weeks. In addition, Clemson has dominated this rivalry over the years, winning six straight against the Seminoles. The Tigers have scored 30 or more points in five straight games against FSU and SportsLine’s model predicts they’ll do so again on Saturday, helping Clemson cover the spread in over 60% of simulations.

Another one of the model’s top college football picks: No. 22 Kentucky (+7) easily stays within the spread when it hosts No. 16 Mississippi State. The Wildcats are coming off consecutive losses in conference games, but the model expects them to respond with a strong effort at home on Saturday night.

Senior quarterback Will Levis missed last week’s game against South Carolina due to an injury and is questionable for Saturday’s game. However, he told the SEC Network that he would be ready to go for this Week 7 matchup. Levis is critical to Kentucky’s success, throwing for more than 1,400 yards along with 12 touchdowns this season.

Mississippi State has only faced one ranked opponent this season, and it came in a home game against Texas A&M two weeks ago. The Bulldogs lost to LSU by 15 points in their previous road game, which is another reason why Kentucky is covering the spread over 60% of the time. See which other teams the model likes here.

How to make college football picks for Week 7

The model has also made the call on who wins and covers in every other FBS matchup in Week 7, and it says a top-15 favorite will go down hard. You can only get every pick for every game at SportsLine.

So what college football picks can you make with confidence? And which top-15 favorite goes down hard? Check out the latest college football odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned almost $3,000 in profit over the past six-plus seasons, and find out.