Week 0 college football picks, odds, 2022 best bets from proven expert: This three-leg parlay returns 6-1

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The 2022 college football season kicks off at noon ET on Saturday with Western Kentucky vs. Austin Peay on CBS Sports Network. Thirty minutes later, the only Power Five vs. Power Five matchup of the day takes place in Dublin, Ireland, when the Nebraska Cornhuskers take on the Northwestern Wildcats. The latest Week 0 college football odds from Caesars Sportsbook list the Cornhuskers at -13.5 in that one.

Elsewhere in the Week 0 college football lines, Illinois is laying 11 points against Wyoming. And Vanderbilt, the only SEC team playing in Week 0, is -8 at Hawaii in the nightcap at 10:30 p.m. ET. Before locking in any college football bets, be sure to see the top Week 0 college football expert picks, predictions and best bets from Barrett Sallee.

Sallee is a true insider — a CBS Sports analyst, SiriusXM host, Heisman voter and consistently one of the top CBS Sports experts picking games against the spread — and his best bets have helped bring in huge returns. He debuted with SportsLine in 2017 and has delivered in a big way on his college football picks

Over the past three years, he is 105-89 in his popular best bets column at SportsLine. Anybody who has been following him is way up.

Now, he has turned his attention to the Week 0 college football odds from Caesars and is sharing his top three best bets over at SportsLine. If you parlay them together, you could be looking at a return of around 6-1. Get his top college football picks now

Top Week 0 college football expert predictions

One of Sallee’s top college football picks for Week 0: He’s backing Illinois (-11) against Wyoming in a 4 p.m. ET matchup on Saturday.

Wyoming was decimated by the transfer portal over the offseason. Top receiver Isaiah Neyor, top running back Xazavian Valladay and quarterbacks Sean Chambers and Levi Williams are all gone.

Illinois is undergoing a change at quarterback as well, but the Illini picked up plenty of Power Five starting experience in landing Tommy DeVito from Syracuse.

Sallee believes Bret Bielema’s Illinois side has enough firepower to put plenty of points on the board. Wyoming, meanwhile, won’t be equipped to keep up with its completely rebuilt offense.

“The combination of DeVito and established offensive skill players will force Wyoming into a shootout … and it isn’t built for that,” he told SportsLine. See who else Sallee likes at SportsLine.

Featured Game | Illinois Fighting Illini vs. Wyoming Cowboys

How to make Week 0 college football picks 

Sallee has also found two other college football picks he’s high on, including a double-digit underdog he believes has a chance to win outright. You can only see his picks at SportsLine.

What are the best bets for Week 0 of college football? And which college football picks need to be part of your parlays? Visit SportsLine now to see Barrett Sallee’s college football best bets, all from one of the top analysts in the nation who has crushed his picks for SportsLine.



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